Alvan R Feinstein

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This article is part of the Tobacco portal on Sourcewatch funded from 2006 - 2009 by the American Legacy Foundation.

Alvan R Feinstein was an Professor of Medicine and epidemiology at Yale University, New Haven, Connecticut who worked diligently for the tobacco industry for most of his lifetime. Researchers have show that he received at least $768,244 from their grant-making bodies between 1976 and 1990.


Carolyn Wells

Documents & Timeline

1980 Jan 14 Ernest Pepples, the chief science-confounder at Brown & Williamson, has send his comments on scientists who are prospective candidates for scientific positions with the Council for Tobacco Research (CTR). None had then been approached and he wants the names of those who made the recommentations to remain anonymous. However he lists them as:

Thought will be given to the issue of how potential candidates will be approached. One possibility would be to commission trusted individuals with industry background to make initial inquiries and visits. Other options would include the use of "headhunter" organisations.

He wants lawyer Edwin Jacob or Leon Jacobsen to be used to make the initial approach to candidates. Alvan R Feinstein's name is scrawled on the page as a possible helper. and he is also included on the list. [2]

1981 Aug 28 Walter O Spitzer and Alvan Feinstein are jointly publishing in the Journal of the American Medical Association (JAMA) a criticism of the use of case-controlled studies: "Coffee and Pancreatic Cancer: The problems of etiologic science and epidemiologic case control researh."

Scientific Hypotheses and 'Fishing Expeditions,'
Most case-control studies are done to check the hypothesis that the target disease has been caused by a specified suspected agent, but after the cases and controls are assembled the investigators can also collect data about many other possible etiologic agents. The process of getting and analyzing data for these other agents is sometimes called a 'fishing expedition,' but the process seems entirely reasonable. If we do not know what causes a disease, we might as well check many different possibilities. On the other hand; when an unsuspected agent yields a positive result, so that the causal hypothesis is generated by the data rather than by the investigator, the results of the fishing expedition requires cautious interpretatation. Many scientists wouldi not even call the positive association a "hypothesis " until the work has been reproduced in another investigation.

The authors of this paper are credited with other publications.

  • Drs Alvan R Feinstein and Ralph I Horwitz from the Robert,Wood Johnson Clinical Scholars Program; Yale University School of Medicine New Haven, Conn
  • Dr Feinstein, also from the Cooperative Studies Program Support Center, Veterans Administration Hospital, West Haven, Conn
  • Dr Walter O Spitzerthe McGill Cancer Center, McGill University.
  • Drs Spitzer and Renaloo N Battista the Kellogg Center for Advanced Studies in. Primary Care, Montreal General Hospital, Montreal.


[Horowitz and Feinstein had already published a number of articles on the same subject:]
  • Feinstein AR Clinical biostististics: XLVIII. Efficacy of different research structures in preventing bias in the,analysis of causation. Clin Pharmacol Ther 1979
  • Horwitz RI, Feinstein AR Methodologic standards and contradictory results in case-control research. Am J Med 1979
  • Feinstein AR: Methodologic problems and standards in case-control research. J Chronie Dis 1979
  • Horwitz RI„ Feinstein AR, Stewart KR Exclusion bias and the false relationship of reserpine/breast,cancer, abstracted. Clin Res 1981
  • Horwitz RI, Feinstein AR, Stremlau JR Alternative data sources and discrepant results in case-control studies of estrogens and endometrial cancer. Am J Epidemiol 1980
  • Horwitz RI, Feinstein AR The problem of 'protopathic bias in case-eontrol studies.; Am J Med
[The Tobacco Institute prepared a major press release exploiting the Spitzer/Feinstein article. The tobacco industry hated case-controlled studies.] [4]

Court-declared list of scientists

Note: this is just a partial list of the scientists, academics and 'consultants' who were being paid via Special Project accounts. It deals only with the scientists known to the courts at the time it was compiled. Many other academics and professionals were paid via these accounts as revealed at later dates.  

The Council of Tobacco Research (CTR) was a tobacco front group designed to promote the idea that science had not proven cigarettes were bad for your health. Those listed below were scientists funded by tobacco to confuse the scientific issues.
Grants made via the CTR's Scientific Advisory Board (SAB) may be legitimate (or not), but those made through the secret Special Account #4 were effectively bribes.
Domingo M Aviado Lauren V Ackerman George Albee James Ballenger
Alvan L Barach Walter L BarkerBroda O Barnes SP#41
W-BRF, Colorado State Uni.
Walter Becker
Peter Berger Rodger L Bick Theodore H Blau Richard Bing
Evelyn J BowersThomas H Brem Irvin Blose Walter M Booker
Oliver Brooke Richard Brotman Lyman A Brewer SP#47
School of Medicine, USC, LA
Barbara B Brown SP#50
PANA Res.Found., Sepulveda CA
K Alexander BrownleeKatherine Bryant Victor B Buhler Thomas H Burford
J Harold BurnMarie Burnett Maurice Campbell Duane Carr
Rune Cederlof Domenic V Cicchetti Martin J Cline W Clark Cooper
Anthony M Cosentino Daniel Cox Gertrude M Cox
Geza De Takato Bertram D Dimmens Charles Dunlap Henry W Elliott
J Earle Estes Frederick J EvansWilliam Evans Hans J Eysenck SP#60/65
Uni of London, UK.
Jack M FarrisSherwin J FeinhandlerAlvan R Feinstein SP#2
Yale Uni, New Haven, Conn
Herman Feldman
Edward Fickes Theodor N Finley Melvin W First Edwin R Fisher
Russel S Fisher Merritt W FosterRichard FreedmanHerbert Freudenberger
Arthur Furst Nicholas GerberMenard M Gertler Jean D Gibbons
Carl GlasserDonald Goodwin Bernard G Greenberg Alan Griffen
Finn Gyntelberg William Heavlin Norman W Heimstra Joseph Herkson
Richard J. Hickey SP#56
Wharton School, U of Penn.
Carlos Hilado Harold C Hodge Charles H Hine
Gary L Huber Wilhelm C Hueper Darrell Huff Duncan Hutcheon
Joseph J Janis Roger A Jenkins Marvin Kastenbaum Marti Kirschbaum
Leonard A Katz SP#3
Michigan State Uni, East Lansing
Lawrence L Kuper Mariano La Via Hiram T Langston SP#4
VA Hospital, Hines IL
William G LeamanMichael Lebowitz Samuel B LehrerWilliam Lerner
Edward Raynar LevineGerald J LiebermanStephen C Littlechild Eleanor Macdonald
Nathan Mantel Ross McFarland Thomas F Mancuso SP#67
Occ.Health, Uni of Pittsburgh
Milton Meckler
Nancy Mello Jack Mendelson Irvin Miller Marc Micozzi
Kenneth M Moser Albert H Niden Judith O'FallonJohn O'Lane
William B OberJoseph H Ogura Ronald OkunIngram Olkin
Thomas L Petty Leslie Preger Walter J. Priest Richard Proctor
Terrence P Pshler Herbert L. RatcliffeAttilio Renzetti L.G.S. Rao
Raymond H Rigdon Jay Roberts Milton B Rosenblatt John Rosencrans
Walter Rosenkrantz Ray H Rosenman Linda Russek Henry Russek
Ragnar Rylander George L Saiger D.E. Sailagyi I Richard Savage
Richard S Schilling Stanley S SchorGerhard N Schrauzer Charles Schultz
John Schwab Carl C Seltzer Paul Shalmy Robert Shilling
Henry Shotwell Allen Silberberg N. Skolnik James F Smith SP#43
Uni of Tennessee, Memphis
Louis A. SoloffSheldon C Sommers (CTR) JB Spalding Charles Spielberg
Charles Spielberger Lawrence Spielvogel Russell StedmanArthur Stein
Elia SterlingTheodor Sterling SP#51/58/61/62
Washington U, St Louis
Thomas Szasz Paul Toannidis
Chris P TsokosHelmut Valentin Richard Wagner Norman Wall
Roger WilsonJack Wiseman George Wright John P Wyatt
Jacob Yerushalmy SP#59
SPH UC Berkely+ Stats, Jerusalem
Irving Zeidman
Aleph Foundation Arthur D. Little Aspen Conference Atmospheric Health Sciences
(Domingo M Avido)
ACVA Atlantic
(Gray Robertson)
Able-Lands Battelle Columbus LaboratoriesBattelle Memorial Institute
Billings & Gussman BioResearch Laboratories
(L.G.S. Rao)
Brigham Young University Colucci & Associates
Cohen Coleghety FoundationCode Consultants Inc.Carney Enterprises Computerland
Engineered Energy ManagementEnvironmental Policy InstituteEysenck Institute of Psychiatry
(Hans J Eysenck)
FudenbergHarvard Medical SchoolHine Inc.
(Charles H Hine)
Information Intersciences
International Consultancy International Technology Corporation International Information Institute J.B. Spalding Statistical Service
J.F. Smith Research Account Jacob, Medinger & Finnegan Kravetz Levine & SpotnitzShook, Hardy & Bacon
Michigan State University Meckler Engineering Group
(Milton Meckler)
Peat, Marwick Main & Co. R.W. Andersohn & Assoc.
Pitney, Hardin & KippPublic Smoking Research Group Response Analysis Project
(Alfred Vogel/Reuben Cohen)
Response Analysis Corporation
(Alfred Vogel/Reuben Cohen)
Schirmer Engineering Corp.St. George Hospital & Medical SchoolStanford Research Institution ProjectFound. for Res. in Bronchial Asthma and Related Diseases
The Futures GroupUniversity of South FloridaWayne State University Weinberg Consulting Group
(Myron Weinberg)
Wisconsin Alumni Research Foundation
DOUBLE-HIDDEN SPECIAL GRANTS paid through the companies/itself
CTR (paid itself) Hearings-Kennedy-Hart BillIndustry Research Liaison Committee Philip Morris
Thomas S Osdene
RJ Reynolds
Murray Senkus
See also [5] and this 1972-81 list with the total amounts paid: [6] This is not an exhaustive list.<br The CTR also has a special site with an index under the Minnesota Agreement. (not very useful) [7]

These are CTR Special Project grantees now known not to have been included in the above list: [8]